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D-果糖-1,6-二磷酸三鈉號(hào):38099-82-0

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D-果糖-1,6-二磷酸三鈉號(hào):38099-82-0穩(wěn)定性強(qiáng)、梯度性好、超越ACS標(biāo)準(zhǔn)、低水分、低蒸發(fā)殘?jiān)V泛應(yīng)用于教學(xué)、科學(xué)研究、分析測(cè)試中,是進(jìn)行化學(xué)實(shí)驗(yàn)、材料分析和精細(xì)化學(xué)品合成所必須的,保證不同批次產(chǎn)品的質(zhì)量穩(wěn)定低紫外吸收背景。

公司提供的D-果糖-1,6-二磷酸三鈉號(hào):38099-82-0*,貨源充足。嚴(yán)格的生產(chǎn)質(zhì)量控制體系,包括:優(yōu)級(jí)純,分析純,化學(xué)純,試劑級(jí),基準(zhǔn)試劑,實(shí)驗(yàn)純,教學(xué)試劑,高純?cè)噭V純,光譜純,電子純。各種包裝規(guī)格,并可提供包裝定制,咨詢(xún)訂購(gòu)
D-果糖-1,6-二磷酸三鈉號(hào):38099-82-0   
英文名稱(chēng):FDP ;D-Fructose-1,6-Phosphate trisodium salt;Harden-Young ester;Hexose diphosphate trisodium salt;D(+)Fructofuranose 1,6-diphosphate trisodium salt    
其他名稱(chēng):1,6-二磷酸果糖三鈉鹽   
號(hào):38099-82-0   
C6H11Na3O12P2=406.06   
級(jí)別:試劑級(jí)   
含量:≥98.0%   
干燥失重:25~28%   
性狀(以下信息僅供參考):白色或類(lèi)白色粉末   
用途:本品僅供科研,不得用于其它用途   
保存:-20℃客戶(hù)根據(jù)D-果糖-1,6-二磷酸三鈉號(hào):38099-82-0性質(zhì)、化學(xué)式、分子式、結(jié)構(gòu)式、比重、密度、號(hào)、沸點(diǎn)、熔點(diǎn)、水溶性、MSDS、用途、作用、規(guī)格包裝、性狀、注意事項(xiàng)、英文名、別稱(chēng)、純度、級(jí)別等情況,本產(chǎn)品化學(xué)性質(zhì)穩(wěn)定,運(yùn)輸條件不苛刻,一般儲(chǔ)存在陰涼,干燥,通風(fēng)良好的地方,遠(yuǎn)離不相容的物質(zhì)。保持容器密閉。
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抗體來(lái)源  Rabbit 
克隆類(lèi)型  polyclonal
交叉反應(yīng)  Human, Mouse, Rat, Dog, Pig, Cow, Guinea Pig, G 
產(chǎn)品類(lèi)型  一抗  磷酸化抗體  
研究領(lǐng)域  腫瘤 免疫學(xué) 神經(jīng)生物學(xué) 細(xì)胞膜受體 新陳代謝 
蛋白分子量  predicted molecular weight: 73kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated Synthesised phosphopeptide derived from human SCNN1B around the phosphorylation site of Ser633
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  Flow-Cyt=1:100-500  IF=1:100-500
(石蠟切片需做抗原修復(fù))
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 SCNN1B is a subunit of the epithelial sodium channel, ENaC. ENac has high sodium selectivity, low conductance, and amiloride sensitivity. The functional channel of ENaC is composed of at least 3 subunits, alpha (SCNN1A), beta (SCNN1B), and gamma (SCNN1G). The 3 subunits show sequence similarities to one another, indicating descent from a common ancestral gene. Each encodes a protein containing 2 transmembrane domains, with intracellular amino and carboxyl termini.
Function : Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Subunit : Probable heterotrimer containing one alpha, one beta and one gamma subunit. A delta subunit D-果糖-1,6-二磷酸三鈉號(hào):38099-82-0can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2. Interacts with the full length immature form of PCSK9 (pro-PCSK9).
Subcellular Location : Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells.
Post-translational modifications : Phosphorylated on serine and threonine residues (By similarity).
DISEASE : Pseudohypoaldosteronism 1, autosomal recessive (PHA1B) [MIM:264350]: A rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. PHA1B is a severe form involving multiple organ systems, and characterized by an often fulminant presentation in the neonatal period with dehydration, hyponatremia, hyperkalemia, metabolic acidosis, failure to thrive and weight loss. Note=The disease is caused by mutations affecting the gene represented in this entry. The degree of channel function impairment differentially affects the renin-aldosterone system and urinary Na/K ratios, resulting in distinct genotype-phenotype relationships in PHA1 patients. Loss-of-function mutations are associated with a severe clinical course and age-dependent hyperactivation of the renin-aldosterone system. This feature is not observed in patients with missense mutations that reduce but do not eliminate channel function. Markedly reduced channel activity results in impaired linear growth and delayed puberty (PubMed:18634878).
Liddle syndrome (LIDDS) [MIM:177200]: Autosomal dominant disorder characterized by pseudoaldosteronism and hypertension associated with hypokalemic alkalosis. The disease is caused by constitutive activation of the renal epithelial sodium channel. Note=The disease is caused by mutations affecting the gene represented in this entry.
Bronchiectasis with or without elevated sweat chloride 1 (BESC1) [MIM:211400]: A debilitating respiratory disease characterized by chronic, abnormal dilatation of the bronchi and other cystic fibrosis-like symptoms in the absence of known causes of bronchiectasis (cystic fibrosis, autoimmune diseases, ciliary dyskinesia, common variable immunodeficiency, foreign body obstruction). Clinical features include sub-normal lung function, sinopulmonary infections, chronic productive cough, excessive sputum production, and elevated sweat chloride in some cases. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity : Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. SCNN1B subfamily.
Database links :
UniProtKB/Swiss-Prot: P51168.2
Entrez Gene: 6338 Human
Omim: 600760 Human
SwissProt: P51168 Human
Unigene: 414614 Human
英文名稱(chēng)  Anti-SPRN
中文名稱(chēng)  新朊蛋白抗體(C端)
別    名  rCG47959; shadow of prion protein; SHO; Protein shadoo; bA108K14.1; C630041J07; FLJ41197; SPRN; Shadow of prion protein precursor; SPRN_MOUSE.
濃    度  1mg/1ml
規(guī) 格  0.2ml/200μg
抗體來(lái)源  Rabbit 
克隆類(lèi)型  polyclonal
交叉反應(yīng)  Mouse, Rat
產(chǎn)品類(lèi)型  一抗   
研究領(lǐng)域  免疫學(xué) 神經(jīng)生物學(xué) 細(xì)胞凋亡 
蛋白分子量  predicted molecular weight: 12kDa
性    狀  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from mouse Shadow(CT)
亞    型  IgG
純化方法  affinity purified by Protein A
儲(chǔ) 存 液  0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
產(chǎn)品應(yīng)用   WB=1:100-500  ELISA=1:500-1000  IP=1:20-100  IHC-P=1:100-500  IHC-F=1:100-500  IF=1:100-500
(石蠟切片需做抗原修復(fù))
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存條件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


 

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