“半胱胺酸蛋白酶蛋白-4抗體，Anti-Caspase 4抗體”應用于IHC、WB、 IF、IP、ELISA，質量保證，無效免費退換，另外本公司生產經營各種標記二抗、免疫印跡常用試劑、免疫組化常用試劑，咨詢！
產品介紹：
【產品名稱】：半胱胺酸蛋白酶蛋白-4抗體，Anti-Caspase 4抗體
【產品類型】：一抗
【產品編號】：BYk-0082R
【相關標記】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【性 狀】： Lyophilized or Liquid
【濃 度】： 1mg/1ml
【亞 型】： IgG
【規 格】：0.1ml/100ug，0.2ml/200ug
【抗體來源】： Rabbit OR MOUSE
【克隆類型】： polyclonal or monoclonal
【產品用途】：科研實驗，用于免疫組化實驗，WB實驗、IF、IP、ELISA實驗，相應的標記抗體有HRP標記抗體，FITC標記，BIO等。
【貯 存】： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
【詳細介紹】：Caspase 4 is a 377 amino acid protein （43 kDa） that belongs to the Ced3/ICE family of cystein proteases. Caspase 4 is an "upstream" caspase with a long prodomain. It undergoes a cleavage upon activation, leading to p20 and p10 subunits which have 67% homology to mature Caspase 1 over the equivalent coding sequences. Caspase 4 is capable of cleaving itself and the p30 Caspase 1 precursor, and of inducing apoptosis in transfected insect or COS cells. In high concentrations, it can also cleave the nuclear DNA enzyme PARP but the biological relevance of this cleavage is unclear. Caspase 4 mRNA is found in most tissues examined with the exception of the brain. Highest expression is found in spleen and lung, with moderate expression in heart and liver. Low expression is observed with skeletal muscle, kidney, and testis.
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